WFU

2015年7月4日 星期六

羅文良醫師 Dr Wen-Liang LO






DDS, School of Dentistry, National Yang-Ming Medical University, 1992.




PhD, Department of Dentistry, School of Dentistry, National Yang-Ming University, 2010




Assistant Professor, School of Dentistry, National Yang-Ming University, 2010~2014




Associate Professor, School of Dentistry, National Yang-Ming University, 2014~




Associate Chair, Department of Dentistry, National Yang-Ming University, 2014~




Attending doctor, Oral & Maxillofacial Surgery, VGH-Taipei. Mar 2003~




Visiting scholar, Oral and Maxillofacial surgery, University of Michigan. Oct 2005 ~Jul 2007




Reviewer of International Journal of Oral and Maxillofacial Surgery, Dec 2007~




Reviewer of Journal of the Chinese Medical Association, March 2009~




Reviewer of Taiwan Journal of Oral and Maxillofacial Surgery, April 2009 ~




Reviewer of PBL case, School of Dentistry, National Yang-Ming University, Aug 2011~ Jul 2013




Reviewer of Journal of Dental Sciences, June 2011~




Reviewer of Journal of Experimental & Clinical Cancer Research, Aug 2013 ~















International papers





1. Chien, Y., Chang, Y. L., Li, H. Y., Larsson, M., Wu, W. W., Chien, C. S., Wang, C. Y., Chu, P. Y., Chen, K. H., Lo, W. L., Chiou, S. H., Lan, Y. T., Huo, T. I., Lee, S. D., Huang, P. I. Synergistic effects of carboxymethyl-hexanoyl chitosan, cationic polyurethane-short branch PEI in miR122 gene delivery: accelerated differentiation of iPSCs into mature hepatocyte-like cells and improved stem cell therapy in a hepatic failure model." Acta Biomater 2015, 13: 228-244.




2. Chien, C. S., Wang, M. L., Chu, P. Y., Chang, Y. L., Liu, W. H., Yu, C. C., Lan, Y. T., Huang, P. I., Lee, Y. Y., Chen, Y. W., Lo, W. L., Chiou, S. H. Lin28B/Let-7 Regulates Expression of Oct4 and Sox2 and Reprograms Oral Squamous Cell Carcinoma Cells to a Stem-like State. Cancer Res. 2015 (SCI) (2012 JCR: IF 8.650; R/C=11/197, Oncology)




3. Yang, M. Y., Chen, M. T., Huang, P. I., Wang, C. Y., Chang, Y. C., Yang, Y. P., Lo, W. L., Sung, W. H., Liao, Y. W., Lee, Y. Y., Chang, Y. L., Tseng, L. M., Chen, Y. W., Ma, H. I. Nuclear Localization Signal-enhanced Polyurethane-Short Branch Polyethylenimine-mediated Delivery of Let-7a Inhibited Cancer Stem-like Properties by Targeting the 3'UTR of HMGA2 in Anaplastic Astrocytoma. Cell Transplant. 2014 (SCI) (2013 JCR: IF 3.570; R/C=9/18, Cell & tissue engineering; R/C=32/122, Medicine, research & experimental; R/C=5/26, Transplantation)




4. Liu WH, Chang YL, Lo WL, Li HY, Hsiao CW, Peng CH, Chiou SH, Ma HI, Chen SJ*. Human induced pluripotent stem cell and nanotechnology-based therapeutics. Cell Transplantation. Oct 8-2014, Epub ahead of print (SCI) (2013 JCR: IF 3.570; R/C=9/18, Cell & tissue engineering; R/C=32/122, Medicine, research & experimental; R/C=5/26, Transplantation)




5. Chang, Y. C., Li, W. C., Twu, N. F., Li, H. Y., Lo, W. L., Chang, Y. L., Lee, Y. Y., Lin, C. F., Shih, Y. H., Chen, M. T. Induction of dental pulp-derived induced pluripotent stem cells in the absence of c-Myc for differentiation into neuron-like cells. J Chin Med Assoc 2014, 77(12): 618-625.




6. Yu EH, Lui MT, Tu HF, Wu CH, Lo WL, Yang CC, Chang KW, Kao SY*. Oral carcinoma with perineural invasion has higher nerve growth factor expression and worse prognosis. Oral Diseases. 2014 20(3): 268-274.(SCI) (2012 JCR: IF 2.377; R/C=17/83, Dentistry, oral surgery & medicine)




7. Yu CC, Tsai LL, Wang ML, Yu CH, Lo WL, Chang YC, Chiou GY, and Chiou SH*. Mir145 targets SOX9/ADAM17 axis to inhibit tumor initiating cells and IL-6-mediated paracrine effects in head and neck cancer. Cancer Research. 2-Apr-2013, online publication; doi:10.1158/0008-5472.CAN-12-3840 (SCI) (2012 JCR: IF 8.650; R/C=11/197, Oncology)




8. Chu PY*, Hu FW, Yu CC, Tsai LL, Yu CH, Wu BC, Chen YW, Huang PI, and Lo WL*. Epithelial-mesenchymal transition transcription factor ZEB1/ZEB2 co-expression predicts poor prognosis and maintains tumor-initiation properties in head and neck cancer. Oral Oncology. 2013 Jan; 49(1): 34-41; 11-Aug-2012, online publication; doi:10.1016/j.oraloncology.2012.07.012 (SCI) (2012 JCR: IF 2.695; R/C=11/83, Dentistry, oral surgery & medicine; R/C=93/197, Oncology)




9. Huang PI, Lo WL, Cherng JY, Chien Y, Chiou GY, and Chiou SH*. Non-viral delivery of RNA interference targeting cancer cells in cancer gene therapy. Current Gene Therapy. 2012, 12, 275-284. (SCI) (2012 JCR: IF 5.318; R/C= 21/161, GENETICS & HEREDITY)




10. Lo WL, Chu PY, Lee TH, Su TL, Chien Y, Chen YW, Huang PI, Tseng LM, Tu PH, Kao SY, and Lo JF*. A combined DNA-Affinic Molecule and N-Mustard Alkylating Agent has an Anti-Cancer Effect and Induces Autophagy in Oral Cancer Cells. International Journal of Molecular Sciences. 2012, 13(3), 3277-3290; doi:10.3390/ijms13033277. Epub 2012 Mar. 9. (SCI) (2012 JCR: IF 2.464; R/C=48/152, CHEMISTRY, MULTIDISCIPLINARY)




11. Lo WL, Chien Y, Chiou GY, Tseng LM, Hsu HS, Chang YL, Lu KH, Chien CS, Wang ML, Chen YW, Huang PI, Hu FW, Yu CC, Chu PY, Chiou SH*. Nuclear localization signal-enhanced RNA interference of EZH2 and Oct4 in the eradication of head and neck squamous cell carcinoma-derived cancer stem cells. Biomaterials. 2012 May;33(14):3693-709. Epub 2012 Feb 21. (SCI) (2012 JCR: IF 7.604; R/C=2/79, ENGINEERING, BIOMEDICAL; R/C=1/27, MATERIALS SCIENCE, BIOMATERIALS)




12. Kao SH, and Lo WL*. Screening for oral cancers – which method is more effective? Journal of the Chinese Medical Association. 2011; 74:529-530. (SCI) (2012 JCR: IF 0.752; R/C=101/155, MEDICINE, GENERAL & INTERNAL)




13. Yang YP, Chien Y, Chiou GY, Cherng JY, Wang ML, Lo WL, Chang YL, Huang PI, Chen YW, Shih YH, Chen MT, Chiou SH*. Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI. Biomaterials. 2012 33: 1462-1476. (SCI) (2012 JCR: IF 7.604; R/C=2/79, ENGINEERING, BIOMEDICAL; R/C=1/27, MATERIALS SCIENCE, BIOMATERIALS)




14. Kuo YL, Tu TY, Chang CF, Li WY, Chang SY, Shiao AS, Chu PY, Chan KT, Tai SK, Wang YF, Kao SC, Kao SY, Lo WL, Wu CH, Shu WH, Ma S, Wang TH*. Extra-major salivary gland pleomorphic adenoma of the head and neck: a 10-year experience and review of the literature. Eur Arch Otorhinolaryngol. 2011; 268(7): 1035-1040. (SCI) (2012 JCR: IF 1.458; R/C=18/44, Otorhinolaryngology)




15. Li-Hsin Chen, Kun-Ling Tsai, Yi-Wei Chen, Cheng-Chia Yu, Kuo-Wei Chang, Shi-Hwa Chiou, Hung-Hai Ku, Pen-Yuan Chu, Ling-Ming Tseng, Pin-I Huang, Wen-Liang Lo*. MicroRNA as a novel modulator in head and neck squamous carcinoma. J Oncol. Volume 2010, Article ID 135632, 15 pages, 2010. Doi:10.1155/2010/135632




16. Cheng-Chia Yu, Yi-Wei Chen, Guang-Yuh Chiou, Lo-Lin Tsai, Pin-I Huang, Charn-Yung Chang, Ling-Ming Tseng, Shih-Hwa Chiou, Sang-Hue Yen, Ming-Yung Chou, Pen-Yuan Chu, Wen-Liang Lo*. MicroRNA let-7a represses chemoresistance and tumorigenicity in head and neck cancer via stem-like properties ablation. Oral Oncol. 2011 March; 47(3):202-210. (SCI) (2012 JCR: IF 2.695; R/C=11/83, Dentistry, oral surgery & medicine; R/C=93/197, Oncology)




17. Wen-Liang Lo, Cheng-Chia Yu, Yi-Wei Chen, Guang-Yuh Chiou, Pin-I Huang, Ling-Ming Tseng, Kai-Hsi Lu, Kuo-Wei Chang, Shiao-Yen Kao, and Shih-Hwa Chiou*. MicroRNA-200c Attenuates Tumour Growth and Metastasis of Presumptive Head and Neck Squamous Cell Carcinoma Stem Cells. J Path. 2011 March; 223(4): 482-495 (SCI) (2012 JCR: IF 7.585; R/C=15/197, Oncology; R/C=3/77, Pathology)




18. Chung-Lan Kao, Liang-Kung Chen, Yuh-Lih Chang, Ming-Chih Yua, Chuan-Chih Hsu,Yu-Chih Chen, Wen-Liang Lo, Shih-Jen Chen, Hung-Hai Ku, and Shin-Jang Hwang. Resveratrol Protects Human Endothelium from H2O2-Induced Oxidative Stress and Senescence via SirT1 Activation. J Atheroscler Thromb. 2010 Sep 30;17(9):970-9. (SCI) (2012 JCR: IF 2.933; R/C= 19/68, Peripheral vascular disease)




19. Hsin-Yang Li, Yi-Jen Chen, Shih-Jen Chen, Chung-Lan Kao, Ling-Ming Tseng, Wen-Liang Lo, Chia-Ming Chang, Der-Ming Yang, Hung-Hai Ku, Nae-Fang Twu, Chen-Yi Liao, Shih-Hwa Chiou ,Yuh-Lih Chang. Induction of Insulin-Producing Cells Derived from Endometrial Mesenchymal Stem-like Cells. J Pharmacol Exp Ther. 2010 Dec;335(3): 817-29. (SCI) (2012 JCR: IF 3.891; R/C= 46/261, Pharmacology and Pharmacy)




20. I-Wei Chen, Kuan-Hsuan Chen, Pin-I Huang, Yu-Chih Chen, Guang-Yu Chiou, Wen-Liang Lo, Ling-Ming Tseng, Han-Sui Hsu, Kuo-Wei Chang, Shih-Hwa Chiou*. Cucurbitacin I Suppressed Stem-like Property and Enhanced Radiation-induced Apoptosis in Head and Neck Squamous Carcinoma-derived CD44+ALDH1+ Cells. Mol Cancer Ther. 2010 Nov; 9(11): 2879-92. Epub 2010 Nov 9. (SCI)(2012 JCR: IF 5.599; R/C= 29/197, Oncology)




21. Cheng-Chia Yu, Wen-Liang Lo, Yi-Wei Chen, Pin-I Huang, Han-Shui Hsu, Ling-Ming Tsen, Shou-Yen Kao, Charn-Jung Chang, and Shih Hwa Chiou. Bmi-1 Regulates Snail Expression and Promotes Metastasis Ability in Head and Neck Squamous Cancer-derived ALDH1 positive Cells. J Oncol. Volume 2011, Article ID 609259, 16 pages. Epub 2010 Sep 27.




22. Wen-Liang Lo, Jian-Yun Lai, Stephen E. Feinberg, Kenji Izumi, Shou-Yen Kao, Che-Shoa Chang, Alan Lin, Huihua Kenny Chiang. Raman spectroscopy monitoring of the cellular activities of a tissue-engineered ex-vivo produced oral mucosal equivalent . J Raman Spec. 2011, 42(2): 174-178 (SCI) (2012 JCR: IF 2.679; R/C= 11/43, Spectroscopy)




23. Yu-Chih Chen, Charn-Jung Chang, Han-Shui Hsu, Yi-Wei Chen, Lung-Kuo Tai, Ling-Ming Tseng, Guang-Yuh Chiou, Shih-Ching Chang, Shou-Yen Kao, Shih-Hwa Chiou, Wen-Liang Lo*. Inhibition of Tumorigenicity and Enhancement of Radiochemosensitivity in Head and Neck Squamous Cancer-derived ALDH1-positive Cells by Knockdown of Bmi-1. Oral Oncol. 2010 Mar; 46(3):158-165. Epub 2009 Dec 29. (SCI) (2012 JCR: IF 2.695; R/C=11/83, Dentistry, oral surgery & medicine; R/C=93/197, Oncology)




24. Yu-Chih Chen, Yi-Wei Chen, Han-Shui Hsu, Ling-Ming Tseng, Pin-I Huang, Kai-Hsi Lu, Lung-Kuo Tai, Ming-Chi Yung, Shih-Ching Chang, Hung-Hai Ku, Shih-Hwa Chiou, Wen-Liang Lo. Aldehyde Dehydrogenase 1 Is a Putative Marker for Cancer Stem Cells in Head and Neck Squamous Cancer. Biochem Biophys Res Commun. 2009 Jul 31;385(3):307-13. Epub 2009 May. (SCI) (2011 JCR: IF 2.484; R/C= 173/290, BIOCHEMISTRY & MOLECULAR BIOLOGY; R/C= 39/74, Biophysics)




25. Chen YW, Yu EH, Wu TH, Lo WL, Li WY, Kao SY. Histopathological factors affecting nodal metastasis in tongue cancer: analysis of 94 patients in Taiwan. Int J Oral Maxillofac Surg. 2008 Oct;37(10):912-6. (SCI) (2009 JCR: IF 1.444; Dentistry, oral surgery & medicine 31/64; Surgery 71/166)




26. Chen YW, Tu HF, Wu TH, Lo WL, Chang CS, Chang KW. Sarcomas and sarcomatoid tumor after radiotherapy of oral squamous cell carcinoma: analysis of 4 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jan;105(1):65-71. (SCI) (2009 JCR: IF 1.499; Dentistry, oral surgery & medicine 29/64)




27. Chu CH, Tu TY, Li AF, Lo WL, Yen CC: Pathology quiz case: Metastatic osteosarcoma of the external auditory canal. Archives of Otolaryngology – Head & Neck Surgery 132(1): 109-110, 2006 (SCI). (2009 JCR: IF 1.918; Otorhinolaryngology 8/36; Surgery 53/166)




28. Yu EH, Lui MT, Chou SJ, Wang SJ, Hung KF, Lo WL, Chang CS, Wu CH, Kao SY: Comparison of Positron Emission Tomography and Computed Tomography for the Detection of Cervical Lymph Node Metastases of Oral Squamous Cell Carcinoma. Asian Journal of Oral & Maxillofacial Surgery 18: 109-115, 2006.




29. Lo WL, Kao SY, Chi LY, Wong YK, Chang RCS: Outcomes of oral squamous cell carcinoma in Taiwan after surgical therapy: factors affecting survival. Journal of Oral & Maxillofacial Surgery 61: 751-758, 2003 (SCI).




30. Lo WL, Chang RCS, Yang AH, Kao SY: Aspergillosis of the temporomandibular joint following irradiation of the parotid region: a case report. International Journal of Oral & Maxillofacial Surgery 32:560-562, 2003 (SCI).




31. Kao SY, Lo WL, Chou J, Yang J, Chou AP, Wong JH, Chang RCS: Hyperbaric oxygen therapy of maxillary osteomyelitis with infection to ethmoid sinus, sphenoid sinus, orbit and base of skull: report of a case. Asian Journal of Oral & Maxillofacial Surgery 13: 55-60, 2001.




Domestic papers


1. Chiu YW, Wu HT, Li WY, Lui MT, Kao SY, Lo WL: primary maxillary leiomyosarcoma - A case report. Taiwan Journal of Oral and Maxillofacial Surgery 22(3): 207-215, 2011.




2. Chiu YW, Wu HT, Chen YW, Lui MT, Kao SY, Lo WL: A giant venous malformation of face and neck – a case report. Taiwan Journal of Oral and Maxillofacial Surgery 22(2): 110-117, 2011.




3. Wu HT, Lai HC, Huang CK, Lui MT, Kao SY, Lo WL: Pediatric Sialolithiasis – a case report and literature review. Taiwan Journal of Oral and Maxillofacial Surgery 21(1): 69-75, 2010.




4. Wu CS, Li YZ, Tu SF, Lo WL, Kao SY, Chang CS: Using microcopic MRI for observation of bone regeneration in animal model. Journal of Dental Science 24:21-29, 2004.




5. Wu CS, Chen YW, Lo WL, Lui MT, Chang CS, Kao SY: The 2002~2003 year cancer bulletin of oral squamous cell carcinoma at oral and maxillofacial surgery in Taipei Veterans General Hospital. Journal of Dental Science 24:15-20, 2004.




6. Wu CH, Kao SY, Lo WL, YX Li, Chang CS: A case report of non-small cell lung cancer metastasizing to oral cavity. Chin J Oral Maxillofac Surg 15: 27-37, March 2004.




7. Lo WL, Chen CQ, Chou SC, Chiang HH, Chang CS: Using light-induced autofluorescent spectrum and images to diagnosis of oral cancers. Journal of Dental Science 22: 103-126, 2002




8. Iou GT, Yang J, Lo WL, Huan TY, Chang CS, Kao SY: Using minocycline sclerosing therapy for the management of chyle leakage after radical neck dissection for a recurrent oral cancer patient. Chinese Journal of Oral and Maxillofacial Surgery 13: 10-18, 2002.




9. Kao SY, Yeung TC, Lo WL, Wu CH, Lui MT, Chang RCS: Rehabilitation of dental implants for the post-irradiated and marginally resected mandible in an oral cancer patient. Chinese Medical Journal (Taipei) 65: 548-552, 2002 (IM).




10. Kao SY, Iou GT, Lo WL, Chang YL, Su CY, Chang CS: An overview of the biocompatible ceramic bone substitue-hydroxyapatite (HA). Chinese Dental Journal 20: 227-242, 2001.




11. Kao SY, Tu HF, Yang J, Lo WL, Chang CS: An overview of the detection and screening of oral cancer and precancer. Chinese Journal of Oral and Maxillofacial Surgery 12: 91-99, 2001.




12. Lo WL, Kao SY, Chang CS: Diagnosis and treatment of internal derangement of temporomadibular joint. J Dent Sci 47:354-360, 2001.




13. Kao SY, Chou J, Lo WL, Yang J, Chou AP, Joe CJ, Chang RCS: Using three-dimension-computerized tomography as a diagnostic tool for temporo-mandibular joint ankylosis: a case report. Chinese Medical Journal (Taipei) 62: 244-249, 1999.




14. Kao SY, Lo WL, Yang J, Jo CJ, Chang RCS: Coronal approach for the replacement of the condylar head in bilateral temporomandibular joint ankylosis: report of three cases. Chinese Medical Journal (Taipei) 62: 388-394, 1999.




15. Kao SY, Lo WL, Jo CJ, Chang CS: Using bicoronal scalp flap to approach TMJs in ankylosing spondylitis patients. Newsletter Assoc Dent Sci ROC. 138: 18-19, Mar. 1999.




16. Lo WL, Kao SY, Chang CS: Necrotizing fasciitis of neck due to odontogenic infection- report of a case. Chinese Journal of Oral and Maxillofacial Surgery 9: 24-32, 1998.




17. Lo WL, Kao SY, Chang CS: Surgical treatment of the temporomandibular disorders. Journal of Dental Science 18: 105-110, 1998.




18. Lo WL, Chang CS: The effects of bone healing of hydroxyappatite and the collagen. Journal of Dental Science 16: 153-156, 1996.





Domestic newsletters



19. Huang HC, Chen YW, Wang LW, Yen SH, Lui MT, Kao SY, Lo WL: Rare case report and its management: atrophy of unilateral parotid gland. Newsletter of Association for Dental Sciences of the Republic of China: No.224, 42-46, 2011




20. Lai HC, Hung SC, Lui MT, Kao SY, Lo WL: Development and application of mesenchymal stem cell in dentistry. Newsletter of Association for Dental Sciences of the Republic of China: No.224, 47-48, 2011




21. Lo WL, Kao SY, Chang CS, Hsu WH: 無菸無酒無檳榔:口腔癌食道癌不會來. 癌症新探: No. 51, 11-19, 2010.




22. Lo WL: Summary report of AAOMS 2007 Research Summit. Monthly Newsletter of the Association for Dental Sciences of ROC: No.207, , 2007.




23. Lo WL, Pai SF, S CR, Kao SY, Lin TW, Chang CS: Establishment of dental digital X ray system in hospital dentistry. Monthly Newsletter of the Taiwan Dental Association: No.25, 16-20, 2006




24. Yu EH, Wu CH, Lo WL, Kao SY, Chang CS: The role of sentinel nodes in head and neck cancers. Monthly Newsletter of the Association for Dental Sciences of ROC: No.193, 32-34, 2005




25. Kao SY, Chen YW, Wu CH, Lo WL, Lui MT, Chang CS: The importance of oral cancer screening. Monthly Newsletter of the Association for Dental Sciences of ROC: No.191, 19-22, 2005




26. Lee YR, Lin SW, Chang C, Lo WL, Kao SY, Chang CS: Using microscopic MRI for observation of bone regeneration in animal model. Monthly Newsletter of the Association for Dental Sciences of ROC: No.190, 40-44, 2005.




27. Kao SY, Chen YW, Wu CS, Lo WL, Lui MT, Chang CS: The importance of screening of oral cancer. Monthly Newsletter of the Association for Dental Sciences of ROC: No.191: 19-22, 2004.




28. Lo WL, Kao SY, Chang CS: Bony ankylosis of the temporomandibular joint – a case report. Monthly Newsletter of the Association for Dental Sciences of ROC: No.175: 43-44, 2002.




29. Chen CK, Lo WL, Kao SY, Chang CS: Mid-face depression with paresthesia after ORIF of zyomatic bone fracture – a case report. Monthly Newsletter of the Association for Dental Sciences of ROC: No.170: 16-17, 2002.




30. Lo WL, Kao SY, Chang CS: The application of PET in head and neck cancers (II). Monthly Newsletter of the Association for Dental Sciences of ROC: No.158: 44-48, 2001.




31. Lo WL, Kao SY, Chang CS: The application of PET in head and neck cancers (I). Monthly Newsletter of the Association for Dental Sciences of ROC: No.157: 34-36, 2000.



Meeting chairperson




7th World Congress on Preventive & Regenerative Medicine, November 4-7, 2014, Chientan Youth Activity Center, Taipei, Taiwan

37th Association for Dental Sciences of the Republic of China Congress “Excellence in Dental Research and Therapy – Footing locally, Thinking globally”, October 24-26, 2014, Kaoshiung Exhibition Center, Kaoshiung, Taiwan

34th Asia Pacific Dental Congress 2012 “Evolution and Harmony for Modern Dentistry”, June 14-18, 2012, Taipei International Conventional Center, Taipei, Taiwan

2013 Annual Meeting & International Conference of Taiwan Head and neck Society, May 4-5, 2013, National Cheng Kung University Hospital, College of Medicine, Tainan, Taiwan

19th Association for Dental Sciences of the Republic of China Congress “New Era of Oral Medicine”, December 20-22, 2013, Taipei International Conventional Center, Taipei, Taiwan

IADR-SEA 28th Annual Scientific Meeting, SEAADE 25th Annual Scientific Meeting, August 11-14, 2014, Borneo Conventional Center Kuching (BCCK), Sarawak, Malaysia








Conference abstract


32. Wen-Liang Lo, Sheng-Ping Hsu, I-Chin Lin, Man-Tien Liu, Shou-Yen Kao. Mandibular reconstruction of severely post-operative jaw deviation with computer-aided surgical simulation (CASS). The 25th Academic Conference of R.O.C. Association of Oral and Maxillofacial Surgery at Taipei, Taiwan, 2013-03-02.




33. Wen-Liang Lo, I-Chin Lin, Yu-Wei Chiu, Man-Tien Liu, Shou-Yen Kao. Immunoglobulin G4-related systemic disease involving mandible: a case report. The 10th Asian Congress on Oral and Maxillofacial Surgery at Bali, Indonesia, 2012-11-16.




34. Wen-Liang Lo, Jian-Yun Lai, Stephen E. Feinberg, Kenji Izumi, Shou-Yen Kao, Che-Shoa Chang, Alan Lin, Huihua Kenny Chiang. Raman spectroscopy monitoring of the cellular activities of a tissue-engineered ex-vivo produced oral mucosal equivalent. The 23rd Academic Conference of R.O.C. Association of Oral and Maxillofacial Surgery at Taipei, Taiwan, 2011-03-12.




35. Yu-Chih Chen, Yi-Wei Chen, Han-Shui Hsu, Ling-Ming Tseng, Pin-I Huang, Kai-Hsi Lu, Lung-Kuo Tai, Ming-Chi Yung, Shih-Ching Chang, Hung-Hai Ku, Shih-Hwa Chiou, Wen-Liang Lo. Aldehyde Dehydrogenase 1 Is a Putative Marker for Cancer Stem Cells in Head and Neck Squamous Cancer. The 22nd Academic Conference of R.O.C. Association of Oral and Maxillofacial Surgery at Tainain, Taiwan, 2010-03-13.­ Best article award.




36. Lo WL, Kao SY: Clinical diagnosis of oral cancers. The 21st Academic Conference of R.O.C. Association of Oral and Maxillofacial Surgery at Taipei, Taiwan, 2009-11-01.




37. Lo WL, Chen DT, Chang KW, Kao SY, Chang CS, Lin A: Creating a self-destructing protein drug, DEVD-sarcin, that causes the apoptotic progression of the oral SAS-tumor. The 21st Academic Conference of R.O.C. Association of Oral and Maxillofacial Surgery at Taipei, Taiwan, 2009-03-07.­ Best article award.




38. Lo WL, Chen CA, Chen DT, Tsai YJ, Chang KW, Chang CS, Lin A: Creating a self-destructing protein drug, DEVD-sarcin, that causes the apoptotic progression of the oral SAS-tumor. The 31st Academic Conference of Association for Dental Sciences of the Republic of China 2008 at Taipei, Taiwan, 2008-11-29.




39. Lo WL, Chen CA, Chen DT, Tsai YJ, Chang KW, Chang CS, Lin A: Creating a self-destructing protein drug, DEVD-sarcin, that causes the apoptotic progression of the oral SAS-tumor. The 8th Asian Congress on Oral and Maxillofacial Surgery 2008 at Thailand, Bangkok, 2008-11-06.




40. Lo WL: “From bench to bedside”- oral mucosa tissue engineering. The 20th Research Conference of Association of Oral and Maxillofacial Surgery of Taiwan at China Medical University, Taichung, 2008-03-15.




41. Chou WW, Lo WL, Lui MT, Kao SY, Chang CS, Wu CH: Epitheloid sarcoma over left buccal area – case report. The 163rd combined case conference of Association of Oral and Maxillofacial Surgery of Taiwan at National Taiwan University Hospital, 2007-09-22.




42. Lo WL: Ex-vivo produced oral mucosal equivalent. Conference of Cancer Therapy Center, Taipei Veterans General Hospital, 2007-09-21.




43. Lo WL, Kao SY, Chang CS: An overview of the detection and screening of oral cancer and precancerous lesions.(The 19th Chinese Medical Congress, Taipei, Taiwan) 2004-06-05




44. Lo WL: Fixture selection (Fixture surface and shape consideration) and wound healing (Bone physiology and healing). Post-graduate lectures in Dental Implants by Dental Scholl, National Yang-Ming University, 2004-04-25




45. Kao SY, Lo WL, Chang CS: 5-year survival of post-surgical patients with oral squamous cell carcinoma at Taipei-VGH. 81th AAOMS (Boston), 1999.




46. Chou AP, Lo WL, Kao SY, Chang CS: Melanoma of oral mucosa-report of a case. Chinese Dent J(Annual Conference).18:30 1999.




47. Lo WL, Kao SY, Chang CS: Internal carotid artery resection & reconstruction due to malignant tumor invasion-a case report. Chinese Dent J(Annual Conference).18:30 1999.




48. Huang TY, Kao SY, Yang CC, Lo WL: Using toluidine blue screening for




early detection of oral squamous cell carcinoma. Chinese Journal of Oral




Maxillofacial Surgery. 11:33 1999




49. Lo WL, Kao SY, Wong YK: Five-year Survival of squamous cell carcinoma




through surgical management at Taipei VGH, Chinese Journal of Oral




Maxillofacial Surgery.11:17 1999




Poster exhibitions





50. Wen-Liang Lo, Dow-Tien Chen, Shou-Yen Kao. Comparative DNA methylation between normal and tumor tissues of the head and neck cancer patients. The 22nd Congress of the European Association for Cranio-Maxillo-Facial Surgery at Prague, Czech Republic, 2014-09-23 ~2014-09-26.




51. Wen-Liang Lo, Dow-Tien Chen, Shou-Yen Kao. Comparative DNA methylation between normal and tumor tissues of the head and neck cancer patients. The 11th Asian Congress on Oral and Maxillofacial Surgery at Xian, China, 2014-08-23.




52. I-Chin Lin, Man-Tien Liu, Shou-Yen Kao, Wen-Liang Lo. Immunoglobulin G4-related systemic disease involving mandible: a case report. The 25th Academic Conference of R.O.C. Association of Oral and Maxillofacial Surgery at Taipei, Taiwan, 2013-03-02.




53. Huang HC, Lui MT, Kao SY, Lo WL: Stenson’s duct obstruction induced parotid gland atrophy. The 25th Academic Conference of R.O.C. Association of Oral and Maxillofacial Surgery at Taipei, Taiwan, 2013-03-02.




54. Lai HC, Lui MT, Kao SY, Lo WL: Hyaluronic acid in the treatment of temporomandibular joint disorders. The 25th Academic Conference of R.O.C. Association of Oral and Maxillofacial Surgery at Taipei, Taiwan, 2013-03-02.




55. I-Chin Lin, Man-Tien Liu, Shou-Yen Kao, Wen-Liang Lo. Immunoglobulin G4-related systemic disease involving mandible: a case report. The 21st Congress of the European Association for Cranio-Maxillo-Facial Surgery at Dubrovnik, Croatia, 2012-09-11 ~2012-09-15 .




56. Huang HC, Chiu YW, Lui MT, Kao SY, Lo WL: Boron neutron capture therapy (BNCT) in recurrent head and neck malignancies: a case report. The 24th Academic Conference of R.O.C. Association of Oral and Maxillofacial Surgery at Taichung, Taiwan, 2012-03-10.




57. Chiu YW, Chen YW, Huang CK, Wu HT, Lui MT, Kao SY, Lo WL: Hemifacial congenital hemangioma: a case report. The 22nd Academic Conference of R.O.C. Association of Oral and Maxillofacial Surgery at Taipei, Taiwan, 2010-03-13.




58. Lin FJ, Huang LJ, Chen YW, Kao SY, Lo WL: A huge teratoma of the infra-temporal and retro-temporomandibular joint region – a case report. The 21st Academic Conference of R.O.C. Association of Oral and Maxillofacial Surgery at Taipei, Taiwan, 2009-03-07.




59. Chou YW, Kao SY, Lo WL, Wu CH, Lui MT: Rehabilitation of dental implants for the post-irradiation and marginally resected mandible in an oral cancer patient. The 21st Academic Conference of R.O.C. Association of Oral and Maxillofacial Surgery at Taipei, Taiwan, 2009-03-07.




60. Lo WL, Chen DT, Chang KW, Kao SY, Chang CS, Lin A: Creating a programmed self-destructing protein drug, PSD-sarcin, that causes the apoptotic progression of the oral SAS-tumor. Asia-Pacific Congress on Oral Cavity Cancer in Conjunction with 12th Annual Meeting of Taiwan Cooperative Oncology Group at Howard International House Taipei, Taiwan, 2008-12-6~7.




61. Chandra M, Wilson RH, Lo WL, Vishwanath K, Izumi K, Feinberg SE, Mycek MA: Sensing metabolic activity in tissue engineered constructs. ECBO 2007: Jun 17th~21st, Munich, Germany.




62. Lo WL, Vishwanath K, Chandra M, Mycek MA, Izumi K, Marcelo C, Feinberg SE: Cell size correlation with flavoprotein endogenous fluorescence in human oral keratinocytes. MTEC 2007: Apr 20th , Ann Arbor, MI U.S.A., 2007




63. Lo WL, Vishwanath K, Chandra M, Mycek MA, Izumi K, Marcelo C, Feinberg SE: Cell size correlation with flavoprotein endogenous fluorescence in human oral keratinocytes. AADR/IADR/CADR 85th General session : Mar 23rd , New Orleans, LA U.S.A., 2007




64. Lo WL, Vishwanath K, Chandra M, Mycek MA, Izumi K, Marcelo C, Feinberg SE: Cell size correlation with flavoprotein endogenous fluorescence in human oral keratinocytes. Research Day, School of Dentistry, U of M : Feb 23rd , Ann Arbor, MI U.S.A., 2007




65. Lo WL, Vishwanath K, Chandra M, Izumi K, Feinberg SE, Marcelo C, Mycek MA: Cell size correlates with flavoprotein endogenous fluorescence in cultured human oral keratinocytes. OWLS 9: Nov 28th, Taipei, Taiwan, R.O.C., 2006




Invited Speech




66. Lo WL: Tissue Engineering/Regenerative Medicine Approach to Soft and Hard Tissue Reconstruction of the Craniomaxillofacial Region. 7th World Congress on Preventive & Regenerative Medicine, Chientan Youth Activity Center, Taipei, Taiwan, 2014-11-07




67. Lo WL: Head and neck cancer stem cells. 36th Asia Pacific Dental Congress at Dubai World Trade Center, Dubai City, United Arab Emirates, 2014-06-19




68. Lo WL: Head and neck cancer stem cells. PBL conference at College of Stomatology, Shanghai Jiao Tong University, Shanghai, China, 2014-05-14




69. Lo WL: Intra-articular injection of hyaluronic acid in TMJ. Annual conference at Shin Kong Wu Ho-Su Memorial Hospital, Taipei City, Taiwan, 2014-04-24




70. Lo WL: Current application of tissue engineering in periodontal regeneration. 19th Association for Dental Sciences of the Republic of China Congress at Taipei International Conventional Center, Taipei City, Taiwan, 2013-12-20




71. Lo WL: Evidence-based systemic factors affecting the implant surgery. 19th Association for Dental Sciences of the Republic of China Congress at Taipei International Conventional Center, Taipei City, Taiwan, 2013-12-20




72. Lo WL, Hsu ML: Introduction of DOSCE of Department of Dentistry, National Yang-Ming University. Implementation of OSCE in clinical oral medicine teaching at Taipei Medical University, Taipei City, Taiwan, 2013-11-23




73. Lo WL: Xerostomia in aged people. Taiwan Academy of Geriatric Dentistry 3rd Scientific Conference at Taipei World Trade Center, Taipei City, Taiwan, 2013-09-07




74. Lo WL: Ex Vivo Produced Oral Mucosal Equivalent: Tissue Engineering from Bench to Bedside. Philippine Dental Association 104th Annual Convention and Scientific Sessions at SMX Convention Center, Manila, Philippines, 2013-04-12




75. Lo WL: TMD’s: surgery or not. Philippine Dental Association 104th Annual Convention and Scientific Sessions at SMX Convention Center, Manila, Philippines, 2013-04-12




76. Lo WL: Change of condylar position after sagittal split osteotomy of mandible. 2012 Autumn Academic meeting of Association of Taiwan Oral and Maxillofacial Surgery at Wan Fang Hospital, Taipei, Taiwan, 2012-10-28




77. Lo WL: Systemic diseases affecting implant surgery. 2012 Academic Conference of the Association of Hospital Dentistry of the Republic of China at Taipei Medical University Hospital, Taipei City, Taiwan, 2013-04-29




78. Lo WL: Contemporary differential diagnosis and management of trigeminal neuralgia. 一般牙科臨床訓練課程-國立陽明大學牙醫臨床教育中心及陽明牙醫校友會, at Taipei, Taiwan, 2011-12-26




79. Lo WL: 64 MDCT in dentistry.Monthly conference of Dental department of Taipei Municipal Hospital, at Taipei, Taiwan, 2011-11-22




80. Lo WL: Prevention and management of complications of impaction and implant surgery. 台北市牙醫師公會100年度學術系列演講, at Taipei, Taiwan, 2011-09-11




81. Lo WL: Prevention and management of complications of impaction surgery. 一般牙科臨床訓練課程-國立陽明大學牙醫臨床教育中心及陽明牙醫校友會, at Taipei, Taiwan, 2011-08-29




82. Lo WL: A long journey for iPS cell-based therapy台北榮民總醫院口腔醫學部, at Taipei, Taiwan, 2011-07-05




83. Lo WL: Emergency treatment in dentistry. 一般牙科臨床訓練課程-國立陽明大學牙醫臨床教育中心及陽明牙醫校友會, at Taipei, Taiwan, 2011-05-30




84. Lo WL: 口腔腫瘤外科治療模式分享-台北榮總經驗. 陽光基金會口腔腫瘤治療團隊座談會, at Taipei, Taiwan, 2011-04-30




85. Lo WL: Implant fixture design (Implant systems), Criteria of selection. 2010 ICOI Fellowship Certify Program, at Taipei, Taiwan, 2011-01-16




86. Lo WL: Healing of wound around dental implant. 2010 ICOI Fellowship Certify Program, at Taipei, Taiwan, 2010-12-16




87. Lo WL: Management of complications of dental implant surgery. 2010 AOCI Taiwan, at Taipei, Taiwan, 2010-10-02




88. Lo WL: The Oral Keratinocytes. 2009 Grand round of the Department of Stomatology at Taipei Veterans General Hospital, Taipei, Taiwan, 2009-11-17




89. Lo WL: Complications in exodontia and its emergent treatment. 2009 Grand round of the Dental Alumni of National Yang-Ming University, Taichung, Taiwan, 2009-07-15




90. Lo WL: Osteoporosis and dental implant. 2009 Grand round of the Dental Association of Pington County, Pington, Taiwan, 2009-05-16




91. Lo WL: Bone augmentation in dental implant. 2009 Grand round of the Dental Association of Pington County, Pington, Taiwan, 2009-05-16




92. Lo WL: Head and neck cancer stem cells. 2009 Grand round of the Department of Dentistry at Taipei Veterans General Hospital, Taipei, Taiwan, 2009-05-12




93. Lo WL: Past, present, and prospect of dental implant. 2009 Grand round of the Department of Internal Medicine at Taipei Veterans General Hospital, Taipei, Taiwan, 2009-04-21




94. Lo WL: Biology and Mechanical Consideration of Distraction Osteogenesis. 2008 Autumn Academic meeting of Association of Chinese Oral and Maxillofacial Surgery at Kaohsiung Medical University, Kaohsiung, Taiwan, 2008-09-21




95. Lo WL: Ex-vivo produced oral mucosa equivalent – A novel platform for gene therapy. Proceedings of 2008 Congress and Scientific Meeting of Chinese Medical Association, at Taipei Veterans General Hospital, Taipei, Taiwan, 2008-06-29




96. Lo WL: Epidemiology and treatment of oral cancers. At Taipei Dental association, 2008-05-18




Certificate





97. Lo WL: Advances in Craniomaxillofacial Distraction Osteogenesis and Resorbable Plate. AO CMF Workshop. At Taoyuan, Taiwan, 2009-06-13, 2009-06-14




98. Lo WL: Qualification of Committee member of IRB. Medical Research Ethics Foundation Seminar. At Taipei, Taiwan, 2008-Aug




99. Lo WL: Advances in Maxillary and Mandibular Reconstruction including Temporomandibular Joint. AO CMF Seminar. At Taoyuan, Taiwan, 2008-06-14









Project





1. Lo WL, et al: Investigation of Stemness-related MicroRNA Signatures in Head and Neck Squamous Cell Carcinoma, NSC 101-2314-B-075-031, 2012




2. Lo WL, et al: Development of Targeting Therapy for Head Neck-derived Cancer Stem Cell and Monitoring the Treatment Effect by Specific Labeling MRI- part 2, VGH-101C-041, 2012




3. Lo WL, et al: Chemoresistance of Head and Neck Squamous Cell Carcinoma Stem-like Cells Depends on Activation of Hsp27, NSC 100-2314-B-075-038, 2011




4. Lo WL, et al: Development of Targeting Therapy for Head Neck-derived Cancer Stem Cell and Monitoring the Treatment Effect by Specific Labeling MRI- part 1, VGH-100C-167, 2011




5. Lo WL, et al: Designing and engineering protein drug based on a new concept of ’programmed self-destructing’ which induced apoptosis of oral cancer cells. Taipei Veterans General Hospital, VGH-99C1-195, 2010




6. Lo WL, et al: Development of protein drug of target therapy against the oral cancer stem cells, Yen Tjing Ling Medical Foundation, CI-98-18, 2009




7. Lo WL, et al: Conditioned production of bioactive insulin from human oral keratinocytes and ex-vivo produced oral mucosal equivalent, VGH-98F-004, 2009




8. Lo WL, et al: Establishment of oral keratinocyte cell bank and fabrication of ex-vivo produced oral mucosal graft, Yen Tjing Ling Medical Foundation, CI-97-18, 2008




9. Lo WL, et al: Real-time monitoring of the ex-vivo produced oral mucosal equivalent with non-invasive Raman spectroscopy, VGH-97F-010, 2008




10. Lo WL, et al: Study of laser-induced autofluorescence spectrum to diagnosing early oral cancer, VGH-B1-167, 2004.




11. Lo WL, et al: Comparison of dental digital image and conventional radiography for the evaluation of peri-implant bony regeneration, VGH-A-63, 2003.




12. Lo WL, et al: Comparison of dental digital image and conventional radiography for the detection of alveolar bony defect , VGH-A-74, 2002.




13. Lo WL, Chang CS, et al: Preliminary evaluation of problem-based learning in dental department of the Taipei Veterans Hospital. VGH-5, 2001.




14. Lo WL, Chang CS, et al: Detection of oral cancer and precancerous lesions with Toluidine blue and its correlations with the tissue pathology. VGH-335, 2001.